N-(1-(2-Aminoethyl)-1H-pyrazol-4-yl)-5-(m-tolyl)oxazole-4-carboxamide → N-(1-(2-Aminoethyl)-1H-imidazol-4-yl)-5-(m-tolyl)oxazole-4-carboxamide

反応式

[NH2:1][CH2:2][CH2:3][N:4]1[CH:8]=[C:7]([NH:9][C:10]([C:12]2[N:13]=[CH:14][O:15][C:16]=2[C:17]2[CH:18]=[C:19]([CH3:23])[CH:20]=[CH:21][CH:22]=2)=[O:11])C=N1.[NH:24]1C=C(N)N=[CH:25]1>>[NH2:1][CH2:2][CH2:3][N:4]1[CH:8]=[C:7]([NH:9][C:10]([C:12]2[N:13]=[CH:14][O:15][C:16]=2[C:17]2[CH:18]=[C:19]([CH3:23])[CH:20]=[CH:21][CH:22]=2)=[O:11])[N:24]=[CH:25]1

参加物

反応物 2

HCID 86704224N-(1-(2-Aminoethyl)-1H-pyrazol-4-yl)-5-(m-tolyl)oxazole-4-carboxamide

HCID 178508046HCID 178508046、化合物

生成物 1

HCID 86704226N-(1-(2-Aminoethyl)-1H-imidazol-4-yl)-5-(m-tolyl)oxazole-4-carboxamide

実験手順

The title compound was synthesized according to above mentioned procedure for N-(1-(2-aminoethyl)-1H-pyrazol-4-yl)-5-(m-tolyl)oxazole-4-carboxamide, starting from 1H-imidazol-4-amine. LC-MS conditions B: tR=0.47 min, [M+H]+=312.29.

出典と根拠

ORDレコード: ord-e8879e42bc2a4430b51a5ebce7aef053
出典データセット: uspto-grants-2016_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09303023B2

反応ノート

読み込み中…