Benzene, 1-bromo-3,5-dimethyl- → 6-(2-Aminoethyl)-5-(3,5-dimethylphenyl)-1,3-dimethyl-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione

HRID 624599ノート

反応式

HRID 624599 の反応式
[NH2:1][CH2:2][CH2:3][N:4]1[C:12](C2C=CC=C(Cl)C=2)=[C:11]2[C:6]([N:7]([CH3:23])[C:8](=[O:22])[N:9]([CH3:21])[C:10]2=[O:20])=[CH:5]1.Br[C:25]1[CH:30]=[C:29]([CH3:31])[CH:28]=[C:27]([CH3:32])[CH:26]=1>>[NH2:1][CH2:2][CH2:3][N:4]1[C:12]([C:25]2[CH:30]=[C:29]([CH3:31])[CH:28]=[C:27]([CH3:32])[CH:26]=2)=[C:11]2[C:6]([N:7]([CH3:23])[C:8](=[O:22])[N:9]([CH3:21])[C:10]2=[O:20])=[CH:5]1

参加物

3

反応物 2

HCID 136357Benzene, 1-bromo-3,5-dimethyl-HCID 867228806-(2-Amino-ethyl)-5-(3-chloro-phenyl)-1,3-dimethyl-1,6-dihydro-pyrrolo[3,4-d]pyrimidine-2,4-dione

生成物 1

HCID 867229206-(2-Aminoethyl)-5-(3,5-dimethylphenyl)-1,3-dimethyl-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione

実験手順

The title compound was prepared analogously to Intermediate B by replacing 1-bromo-3-chlorobenzene with 1-bromo-3,5-dimethylbenzene;

出典と根拠

ORDレコード
ord-5a227009cea84688a69d34ade3af5fa5
出典データセット
uspto-grants-2016_04
特許番号
US09303035B2

反応ノート

読み込み中…