1-Isopropylhydrazine hydrochloride → 9-Bromo-2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine

HRID 624641ノート

反応式

HRID 624641 の反応式
[Br:1][C:2]1[CH:21]=[CH:20][C:5]2[C:6]3[N:7]([CH:11]=[C:12]([C:14]([NH:16][C:17](=[NH:19])[CH3:18])=O)[N:13]=3)[CH2:8][CH2:9][O:10][C:4]=2[CH:3]=1.Cl.[CH:23]([NH:26]N)([CH3:25])[CH3:24]>C(O)(=O)C>[Br:1][C:2]1[CH:21]=[CH:20][C:5]2[C:6]3[N:7]([CH:11]=[C:12]([C:14]4[N:26]([CH:23]([CH3:25])[CH3:24])[N:19]=[C:17]([CH3:18])[N:16]=4)[N:13]=3)[CH2:8][CH2:9][O:10][C:4]=2[CH:3]=1

参加物

4

反応物 2

HCID 855731-Isopropylhydrazine hydrochlorideHCID 1357436659-bromo-N-(1-iminoethyl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine-2-carboxamide

生成物 1

HCID 582043229-Bromo-2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

9-Bromo-N-(1-iminoethyl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine-2-carboxamide 29 was reacted with isopropylhydrazine hydrochloride 4 in acetic acid to give III.

出典と根拠

ORDレコード
ord-5d571b1286f942ebbc18b331a524c739
出典データセット
uspto-grants-2016_04
特許番号
US09303043B2

反応ノート

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