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2-[(2-Nitrophenyl)sulfanyl]benzoic acid → 2-((2-Aminophenyl)thio)benzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-[(2-Nitrophenyl)sulfanyl]benzoic acid | HCID 376978 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethyl Acetate | HCID 8857 | — |
| 生成物 | 2-((2-Aminophenyl)thio)benzoic acid | HCID 10955828 | — |
反応手順
To a solution of 2-((2-nitrophenyl)thio)benzoic acid, prepared as described in the previous step, (43.3 g, 0.157 mol) in ethyl acetate (500 mL) was added Pd/C (8 g). The reaction solution was stirred at room temperature overnight under hydrogen gas atmosphere. The mixture was filtered and concentrated to provide the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09304126B2 |
| 出典データセット | uspto-grants-2016_04 |
| ORD ID | ord-91e47b447afe49b2be3082fc09c284fa |
| 出典メモ | uspto-grants-2016_04 |