Ammonia → 1-(4-Amino-3-nitrophenyl)propan-1-one
反応式
[N+:1]([C:4]1[CH:9]=[C:8]([C:10](=[O:13])[CH2:11][CH3:12])[CH:7]=[CH:6][C:5]=1[NH:14]C(=O)C)([O-:3])=[O:2].N>Cl>[NH2:14][C:5]1[CH:6]=[CH:7][C:8]([C:10](=[O:13])[CH2:11][CH3:12])=[CH:9][C:4]=1[N+:1]([O-:3])=[O:2]参加物
4
実験手順
A solution of N-(2-nitro-4-propionylphenyl)acetamide (3.36 g, 10 mmol) in 30 mL 35% HCl was heated to reflux for 1 h and cooled. The pH was adjusted to 7 by adding aqueous ammonia under stirring. The precipitate was collected by filtration to give the desired product as a yellow solid (1.75 g, 90%).
後処理
- temperatureto reflux for 1 h
- temperaturecooled
- filtrationThe precipitate was collected by filtration
出典と根拠
- ORDレコード
- ord-ea8c148e812047ff9dc1cf4ef97d453b
- 出典データセット
- uspto-grants-2016_04
- 特許番号
- US09309211B2
反応ノート
読み込み中…