N(C(OCCOC)=O)=NC(OCCOC)=O.[CH3:17][C:18]1[CH:23]=[C:22]([N+:24]([O-:26])=[O:25])[C:21]([CH3:27])=[CH:20][C:19]=1[OH:28].[CH:29]1([CH:32](O)[CH3:33])[CH2:31][CH2:30]1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C(=O)(O)[O-].[Na+]>C1(C)C=CC=CC=1>[CH:29]1([CH:32]([O:28][C:19]2[CH:20]=[C:21]([CH3:27])[C:22]([N+:24]([O-:26])=[O:25])=[CH:23][C:18]=2[CH3:17])[CH3:33])[CH2:31][CH2:30]13.10 g of Bis(2-methoxyethyl) azodicarboxylate was added to a mixture of 1.70 g of 2,5-dimethyl-4-nitrophenol, 0.88 g of (1-cyclopropyl) ethanol, 3.20 g of triphenylphosphine and 100 mL of toluene at 0° C., and the mixture was stirred at 80° C. for 4 hours. After cooling, a saturated aqueous sodium bicarbonate solution was added, and the mixture was extracted with ethyl acetate, and then the organic layer was washed with water and saturated salt water and dried over anhydrous magnesium sulfate. The resulting residue was subjected to silica gel column chromatography to obtain 1.09 g of 1-(1-cyclopropylethoxy)-2,5-dimethyl-4-nitrobenzene.
読み込み中…
