(S)-N-((S)-1-(3-isopropylphenyl)ethyl)-2-methylpropane-2-sulfinamide → (1S)-1-[3-(Methylethyl)phenyl]ethylamine

反応式

[CH:1]([C:4]1[CH:5]=[C:6]([C@@H:10]([NH:12][S@](C(C)(C)C)=O)[CH3:11])[CH:7]=[CH:8][CH:9]=1)([CH3:3])[CH3:2]>CO>[CH:1]([C:4]1[CH:5]=[C:6]([C@@H:10]([NH2:12])[CH3:11])[CH:7]=[CH:8][CH:9]=1)([CH3:3])[CH3:2]

参加物

実験手順

The mixture of (S)—N—((S)-1-(3-isopropylphenyl)ethyl)-2-methylpropane-2-sulfinamide (6.1 g, 0.023 mol) in methanol was stirred at room temperature for 3 hours and then concentrated and evaporated with toluene for three times to give the titled compound which was without purification for next step.

後処理

concentrationconcentrated
customevaporated with toluene for three times

出典と根拠

ORDレコード: ord-6aa35cfe6d984e308516c2debcf98c03
出典データセット: uspto-grants-2016_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09309227B2

反応ノート

読み込み中…

参加物

反応物 1

HCID 86732637(S)-N-((S)-1-(3-isopropylphenyl)ethyl)-2-methylpropane-2-sulfinamide

生成物 1

HCID 86674570(1S)-1-[3-(Methylethyl)phenyl]ethylamine

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

後処理

concentrationconcentrated
customevaporated with toluene for three times

出典と根拠

ORDレコード: ord-6aa35cfe6d984e308516c2debcf98c03
出典データセット: uspto-grants-2016_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09309227B2

反応ノート

読み込み中…