Isopropyl iodide → 3-Isopropylsulfanyl-pyrazine-2-carboxylic acid methyl ester
反応式
[CH3:1][O:2][C:3]([C:5]1[C:10]([SH:11])=[N:9][CH:8]=[CH:7][N:6]=1)=[O:4].I[CH:13]([CH3:15])[CH3:14]>>[CH3:1][O:2][C:3]([C:5]1[C:10]([S:11][CH:13]([CH3:15])[CH3:14])=[N:9][CH:8]=[CH:7][N:6]=1)=[O:4]参加物
3
実験手順
3-Mercapto-pyrazine-2-carboxylic acid methyl ester (0.35 g, 2.0 mmol) obtained in Step A and 2-iodopropane were reacted in the same manner as in Step A of Preparation Example 5 to obtain the title compound (0.267 g, 61%).
出典と根拠
- ORDレコード
- ord-9c6637ca917049fabc1a23509cbfe685
- 出典データセット
- uspto-grants-2016_09
- 特許番号
- US09447044B2
反応ノート
読み込み中…