化工社化工社 化学情報印刷レポート · 研究参考用
Formaldehyde → (3-chloro-2H-indazol-2-yl)methanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Formaldehyde | HCID 712 | — |
| 反応物 | 3-Chloro-1H-indazole | HCID 95894 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | (3-chloro-2H-indazol-2-yl)methanol | HCID 59589510 | 99.7% |
反応手順
In a 250 mL round bottom flask, 3-chloro-2H-indazole (1.95 g, 10 mmol), 30% HCHO (2 mL, 20 mmol) were mixed in water (10 mL). The reaction mixture was refluxed for 2 hours. After cooling down to room temperature, the solid was filtered, washed with water, and dried under vacuum to provide (3-chloro-2H-indazol-2-yl)methanol (1.82 g, 99% yield).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09315521B2 |
| 出典データセット | uspto-grants-2016_04 |
| ORD ID | ord-df448b7d99c644bc9ce7349e01de42a3 |
| 出典メモ | uspto-grants-2016_04 |