Nitromethane → 4-nitro-1,3-diphenylbutan-1-one
反応式
[CH:1](=[CH:8][C:9]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N+:17]([CH3:20])([O-:19])=[O:18].C(NCC)C>CO>[N+:17]([CH2:20][CH:1]([C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[CH2:8][C:9]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[O:10])([O-:19])=[O:18]参加物
5
実験手順
In a 1 L flask, 94.7 g (0.455 mol) of benzylideneacetophenone were dissolved in 600 g of methanol, admixed with 138.9 g (2.275 mol) of nitromethane and 166.4 g (2.275 mol) of diethylamine and refluxed for 16 h. The solvent was half distilled off in vacuo and the precipitated solid was separated off and dried to constant weight in vacuo to obtain 118 g (438 mmol) of 4-nitro-1,3-diphenylbutan-1-one.
後処理
- temperaturerefluxed for 16 h
- distillationdistilled off in vacuo
- customthe precipitated solid was separated off
- customdried to constant weight in vacuo
出典と根拠
- ORDレコード
- ord-b37301f462d643e39a5b4a56c75d255a
- 出典データセット
- uspto-grants-2016_04
- 特許番号
- US09317012B2
反応ノート
読み込み中…