5-(1-Methoxy-2-methylpropan-2-yl)-1,2-oxazol-3-amine → Phenyl 5-(1-methoxy-2-methylpropan-2-yl)isoxazol-3-ylcarbamate
反応式
[CH3:1][O:2][CH2:3][C:4]([C:7]1[O:11][N:10]=[C:9]([NH2:12])[CH:8]=1)([CH3:6])[CH3:5].C(C1C=C(N[C:22](=[O:30])[O:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)ON=1)(C)C>>[CH3:1][O:2][CH2:3][C:4]([C:7]1[O:11][N:10]=[C:9]([NH:12][C:22](=[O:30])[O:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH:8]=1)([CH3:6])[CH3:5]参加物
3
実験手順
Prepared from 5-(1-methoxy-2-methylpropan-2-yl)isoxazol-3-amine (30 mg, 0.176 mmol) according to the method described for phenyl 3-isopropylisoxazol-5-ylcarbamate in Example 122A Step 3, to afford phenyl 5-(1-methoxy-2-methylpropan-2-yl)isoxazol-3-ylcarbamate as an oil (50 mg, 98%). 1H NMR (300 MHz, CDCl3) δ 8.04 (brs, 1H), 7.42-7.43 (m, 2H), 7.31 (m, 1H), 7.18-7.21 (m, 2H), 6.63 (s, 1H), 3.45 (s, 2H), 3.33 (s, 3H), 1.35 (s, 6H).
出典と根拠
- ORDレコード
- ord-8212d6ac06c642a2aea260f6dbbb07e9
- 出典データセット