化工社化工社 化学情報印刷レポート · 研究参考用
5,8,11,14,17-Eicosapentaenoic Acid → 5,8,11,14,17-Eicosapentaenoyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5,8,11,14,17-Eicosapentaenoic Acid | HCID 3209 | — |
| 反応物 | Oxalyl chloride | HCID 65578 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | 5,8,11,14,17-Eicosapentaenoyl chloride | HCID 54084548 | — |
反応手順
To a solution of 605 mg of 5,8,11,14,17-eicosapentaenic acid 11 in 6 ml of dry chloroform was added 0.25 ml of oxalyl chloride under argon at room temperature. The mixture was reacted for 2 hours. From the reaction mixture were removed the chloroform and the remaining oxalyl chloride by distillation under reduced pressure to give 5,8,11,14,17-eicosapentaenoyl chloride 12, which was then directly used for the next step.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09321716B1 |
| 出典データセット | uspto-grants-2016_04 |
| ORD ID | ord-425b402c6c2949728cc352e8914727f2 |
| 出典メモ | uspto-grants-2016_04 |