6-(3-Chlorophenyl)picolinic acid → 6-(3-Chloro-phenyl)-pyridine-2-carboxylic acid (1-dimethylcarbamoyl-1-ethyl-propyl)-amide

HRID 631994ノート

反応式

HRID 631994 の反応式
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[N:13]=[C:12]([C:14]([OH:16])=O)[CH:11]=[CH:10][CH:9]=2)[CH:5]=[CH:6][CH:7]=1.[NH2:17][C:18]([CH2:26][CH3:27])([CH2:24][CH3:25])[C:19]([N:21]([CH3:23])[CH3:22])=[O:20]>>[CH3:23][N:21]([CH3:22])[C:19]([C:18]([NH:17][C:14]([C:12]1[CH:11]=[CH:10][CH:9]=[C:8]([C:4]2[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=2)[N:13]=1)=[O:16])([CH2:24][CH3:25])[CH2:26][CH3:27])=[O:20]

参加物

3

反応物 2

HCID 247301356-(3-Chlorophenyl)picolinic acidHCID 798102892-amino-2-ethyl-N,N-dimethyl-butyramide

生成物 1

HCID 711055436-(3-Chloro-phenyl)-pyridine-2-carboxylic acid (1-dimethylcarbamoyl-1-ethyl-propyl)-amide

実験手順

The title compound was synthesized in analogy to Example 1, using 6-(3-chlorophenyl)-2-pyridinecarboxylic acid (CAN 863704-38-5) and 2-amino-2-ethyl-N,N-dimethyl-butyramide as starting materials, MS (EI): 374.2 [M+H]+.

出典と根拠

ORDレコード
ord-5ecfcbf4e87c4fe0a475f49618cdf90e
出典データセット
uspto-grants-2016_04
特許番号
US09321727B2

反応ノート

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