6-(3-Chloro-phenyl)-5-methyl-pyridine-2-carboxylic acid → 6-(3-Chloro-phenyl)-5-methyl-pyridine-2-carboxylic acid (1-methyl-1-oxazol-2-yl-ethyl)-amide

HRID 632048ノート

反応式

HRID 632048 の反応式
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[N:13]=[C:12]([C:14]([OH:16])=O)[CH:11]=[CH:10][C:9]=2[CH3:17])[CH:5]=[CH:6][CH:7]=1.[CH3:18][C:19]([CH3:26])([C:21]1[O:22][CH:23]=[CH:24][N:25]=1)[NH2:20]>>[CH3:18][C:19]([NH:20][C:14]([C:12]1[CH:11]=[CH:10][C:9]([CH3:17])=[C:8]([C:4]2[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=2)[N:13]=1)=[O:16])([C:21]1[O:22][CH:23]=[CH:24][N:25]=1)[CH3:26]

参加物

3

反応物 2

HCID 710878026-(3-Chloro-phenyl)-5-methyl-pyridine-2-carboxylic acidHCID 82418817alpha,alpha-Dimethyl-2-oxazolemethanamine

生成物 1

HCID 711055646-(3-Chloro-phenyl)-5-methyl-pyridine-2-carboxylic acid (1-methyl-1-oxazol-2-yl-ethyl)-amide

実験手順

The title compound was synthesized in analogy to Example 1, using 6-(3-chloro-phenyl)-5-methyl-pyridine-2-carboxylic acid and α,α-dimethyl-2-oxazolemethanamine (CAN 1211519-76-4) as starting materials, MS (EI): 356.1 (M+H)+.

出典と根拠

ORDレコード
ord-1d44ded97fba459783e835665ee5e546
出典データセット
uspto-grants-2016_04
特許番号
US09321727B2

反応ノート

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