化工社化工社 化学情報印刷レポート · 研究参考用
Methyl 2-amino-2-ethylbutanoate hydrochloride → 2-([5-[Bis-(2,2,2-trifluoro-ethyl)-amino]-6-cyclopropylmethoxy-pyridine-2-carbonyl]-amino)-2-ethyl-butyric acid methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl 2-amino-2-ethylbutanoate hydrochloride | HCID 75488114 | — |
| 反応物 | 5-[Bis-(2,2,2-trifluoro-ethyl)-amino]-6-cyclopropylmethoxy-pyridine-2-carboxylic acid | HCID 86674774 | — |
| 生成物 | 2-([5-[Bis-(2,2,2-trifluoro-ethyl)-amino]-6-cyclopropylmethoxy-pyridine-2-carbonyl]-amino)-2-ethyl-butyric acid methyl ester | HCID 71491228 | — |
反応手順
The title compound was synthesized in analogy to Example 1, using 5-[bis-(2,2,2-trifluoro-ethyl)-amino]-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 162 b) and methyl 2-amino-2-ethylbutanoate hydrochloride (CAN 92398-54-4) as starting materials, MS (EI): m/e=500.1 [M+H]+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09321727B2 |
| 出典データセット | uspto-grants-2016_04 |
| ORD ID | ord-f0e4b020be8346798e53184a46eed5fa |
| 出典メモ | uspto-grants-2016_04 |