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HRID 632286作成日：2026年10月26日

(2S)-2-amino-N,4,4-trimethyl-pentanamide → 6-(Tetrahydro-pyran-4-ylmethoxy)-5-trifluoromethyl-pyridine-2-carboxylic acid ((S)-3,3-dimethyl-1-methylcarbamoyl-butyl)-amide

https://huagongshe.com/reaction/632286

反応式

関与物質

役割名称HCID仕込み量
反応物(2S)-2-amino-N,4,4-trimethyl-pentanamideHCID 57635521—
反応物6-((Tetrahydro-2H-pyran-4-yl)methoxy)-5-(trifluoromethyl)picolinic acidHCID 71087388—
生成物6-(Tetrahydro-pyran-4-ylmethoxy)-5-trifluoromethyl-pyridine-2-carboxylic acid ((S)-3,3-dimethyl-1-methylcarbamoyl-butyl)-amideHCID 71105659—

反応手順

The title compound was synthesized in analogy to Example 1, using 6-((tetrahydro-2H-pyran-4-yl)methoxy)-5-(trifluoromethyl)picolinic acid and (2S)-2-amino-N,4,4-trimethyl-pentanamide (CAN 1160161-70-5) as starting materials, MS (EI): m/e=446.4 [M+H]+.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US09321727B2
出典データセットuspto-grants-2016_04
ORD IDord-9b3f5e3b0bb1419c8fe1a03df3b8c258
出典メモuspto-grants-2016_04