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HRID 632290作成日:2026年10月26日

(2S)-2-amino-N,4,4-trimethyl-pentanamide → 6-Cyclopropylmethoxy-5-(6-oxa-1-aza-spiro[3.3]hept-1-yl)-pyridine-2-carboxylic acid ((S)-3,3-dimethyl-1-methylcarbamoyl-butyl)-amide

https://huagongshe.com/reaction/632290

反応式

関与物質

役割名称HCID仕込み量
反応物(2S)-2-amino-N,4,4-trimethyl-pentanamideHCID 57635521—
反応物6-(Cyclopropylmethoxy)-5-(6-oxa-1-azaspiro[3.3]heptan-1-yl)picolinic acidHCID 71087704—
生成物6-Cyclopropylmethoxy-5-(6-oxa-1-aza-spiro[3.3]hept-1-yl)-pyridine-2-carboxylic acid ((S)-3,3-dimethyl-1-methylcarbamoyl-butyl)-amideHCID 71113055—

反応手順

The title compound was synthesized in analogy to Example 1, using 6-(cyclopropylmethoxy)-5-(6-oxa-1-azaspiro[3.3]heptan-1-yl)picolinic acid and (2S)-2-amino-N,4,4-trimethyl-pentanamide (CAN 1160161-70-5) as starting materials. MS (EI): m/e=431.1 [M+H]+.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US09321727B2
出典データセットuspto-grants-2016_04
ORD IDord-c285b028ec5245af96abe8fe4a1b0644
出典メモuspto-grants-2016_04