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HRID 632318作成日：2026年10月26日

Methylamine hydrochloride → 6-Cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carboxylic acid (1-ethyl-1-methylcarbamoyl-propyl)-amide

https://huagongshe.com/reaction/632318

反応式

関与物質

役割名称HCID仕込み量
反応物Methylamine hydrochlorideHCID 6364545—
反応物2-(6-(Cyclopropylmethoxy)-5-(trifluoromethyl)picolinamido)-2-ethylbutanoic acidHCID 71087462—
生成物6-Cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carboxylic acid (1-ethyl-1-methylcarbamoyl-propyl)-amideHCID 71093527—

反応手順

The title compound was synthesized in analogy to Example 1, using 2-(6-(cyclopropylmethoxy)-5-(trifluoromethyl)picolinamido)-2-ethylbutanoic acid and methanamine hydrochloride as starting materials. MS (EI): m/e=388.0 [M+H]+.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US09321727B2
出典データセットuspto-grants-2016_04
ORD IDord-bf0a36facefe4e6bba36c5cd546983c1
出典メモuspto-grants-2016_04