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HRID 632340作成日：2026年10月26日

5-Bromo-6-(3-methyl-oxetan-3-ylmethoxy)-pyridine-2-carboxylic acid → 5-Bromo-6-(3-methyl-oxetan-3-ylmethoxy)-pyridine-2-carboxylic acid (3-thiazol-2-yl-oxetan-3-yl)-amide

https://huagongshe.com/reaction/632340

反応式

関与物質

役割名称HCID仕込み量
反応物5-Bromo-6-(3-methyl-oxetan-3-ylmethoxy)-pyridine-2-carboxylic acidHCID 71087890—
反応物3-(1,3-Thiazol-2-yl)oxetan-3-amine hydrochlorideHCID 86674782—
生成物5-Bromo-6-(3-methyl-oxetan-3-ylmethoxy)-pyridine-2-carboxylic acid (3-thiazol-2-yl-oxetan-3-yl)-amideHCID 71113131—

反応手順

The title compound was synthesized in analogy to Example 280c, using 5-bromo-6-(3-methyl-oxetan-3-ylmethoxy)-pyridine-2-carboxylic acid (Example 280b) and 3-(thiazol-2-yl)oxetan-3-amine hydrochloride (Example 281b) as starting materials, MS (EI): m/e=440.4 [M+H]+.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US09321727B2
出典データセットuspto-grants-2016_04
ORD IDord-34a03e27d0a8447692ff8a0a6ce29930
出典メモuspto-grants-2016_04