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HRID 632440作成日：2026年10月26日

(2S)-2-amino-N,4,4-trimethyl-pentanamide → 5-Cyclopropyl-6-(2-methyl-propane-1-sulfonyl)-pyridine-2-carboxylic acid ((S)-3,3-dimethyl-1-methylcarbamoyl-butyl)-amide

https://huagongshe.com/reaction/632440

反応式

関与物質

役割名称HCID仕込み量
反応物(2S)-2-amino-N,4,4-trimethyl-pentanamideHCID 57635521—
反応物5-Cyclopropyl-6-(isobutylsulfonyl)picolinic acidHCID 71087731—
生成物5-Cyclopropyl-6-(2-methyl-propane-1-sulfonyl)-pyridine-2-carboxylic acid ((S)-3,3-dimethyl-1-methylcarbamoyl-butyl)-amideHCID 71105749—

反応手順

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-(isobutylsulfonyl)picolinic acid (Example 351 b) and (2S)-2-amino-N,4,4-trimethyl-pentanamide (CAN 1160161-70-5) as starting materials. MS (EI): m/e=424.6 [M+H]+.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US09321727B2
出典データセットuspto-grants-2016_04
ORD IDord-0400da0c6d9b45879690ee3c2620a23c
出典メモuspto-grants-2016_04