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HRID 632444作成日：2026年10月26日

(S)-2,2,2-Trifluoro-1-(pyridin-3-YL)ethanamine hydrochloride → 5-Cyclopropyl-6-(2-methyl-propane-1-sulfonyl)-pyridine-2-carboxylic acid ((S)-2,2,2-trifluoro-1-pyridin-3-yl-ethyl)-amide

https://huagongshe.com/reaction/632444

反応式

関与物質

役割名称HCID仕込み量
反応物(S)-2,2,2-Trifluoro-1-(pyridin-3-YL)ethanamine hydrochlorideHCID 51358484—
反応物5-Cyclopropyl-6-(isobutylsulfonyl)picolinic acidHCID 71087731—
生成物5-Cyclopropyl-6-(2-methyl-propane-1-sulfonyl)-pyridine-2-carboxylic acid ((S)-2,2,2-trifluoro-1-pyridin-3-yl-ethyl)-amideHCID 71105750—

反応手順

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-(isobutylsulfonyl)picolinic acid (Example 351 b) and (S)-2,2,2-trifluoro-1-(pyridin-3-yl)ethanamine hydrochloride (CAN 336105-46-5) as starting materials. MS (EI): m/e=442.4 [M+H]+.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US09321727B2
出典データセットuspto-grants-2016_04
ORD IDord-d5a9286e68084d88b1121a74b15d230b
出典メモuspto-grants-2016_04