L-tert-Leucine → (2S)-2-Amino-3,3-dimethylbutanamide

HRID 6329

反応式

HRID 6329 の反応式
[NH2:1][CH:2]([C:7]([NH2:9])=[O:8])[C:3]([CH3:6])([CH3:5])[CH3:4].N[C@H](C(O)=O)C(C)(C)C.N[C@@H](C(N)=O)C(C)(C)C>>[NH2:1][C@H:2]([C:7]([NH2:9])=[O:8])[C:3]([CH3:6])([CH3:5])[CH3:4]

参加物

4

反応物 3

HCID 164608L-tert-LeucineHCID 34964442-Amino-3,3-dimethylbutanamideHCID 10197708(2R)-2-Amino-3,3-dimethylbutanamide

生成物 1

HCID 11297986(2S)-2-Amino-3,3-dimethylbutanamide

実験手順

In the same way as in example VIII, an incubation was carried out with DL-tertiary leucine amide. Analysis of the remaining reaction mixture after 8 hours showed that both L-tertiary leucine and D-tertiary leucine amide with an e.e. of ≥99% were present in the reaction mixture.

後処理

  1. customAnalysis of the remaining reaction mixture after 8 hours

出典と根拠

ORDレコード
ord-ea88f85ac3924f1abb143061996c57cd
出典データセット
uspto-grants-1993_09
特許番号
US05248608

関連ノート

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