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HRID 633262作成日：2026年10月25日

1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acid → N-(4-chloro-3-(pyridin-2-yl)phenyl)-1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxamide

https://huagongshe.com/reaction/633262

反応式

関与物質

役割名称HCID仕込み量
反応物1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acidHCID 4270263—
反応物4-Chloro-3-(pyridin-2-yl)anilineHCID 40151925—
生成物N-(4-chloro-3-(pyridin-2-yl)phenyl)-1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxamideHCID 58614761—

反応手順

50 mg of 4-chloro-3-(pyridin-2-yl)aniline was coupled to 1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acid via Procedure G. The product was purified on reverse phase HPLC to yield N-(4-chloro-3-(pyridin-2-yl)phenyl)-1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxamide. MS (Q1) 407.0 (M)+.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US09321761B2
出典データセットuspto-grants-2016_04
ORD IDord-21a1045fadf041578ac9f60371201b3a
出典メモuspto-grants-2016_04