p-Toluenesulfonic acid monohydrate → 2-(2-chloro-4-((4-(((7R,8aS)-5,5-dimethyloctahydroindolizin-7-yl)amino)-5-fluoropyrimidin-2-yl)amino)phenoxy)ethan-1-ol
反応式
[NH2:1][C:2]1[CH:11]=[CH:10][C:5]([O:6][CH2:7][CH2:8][OH:9])=[C:4]([Cl:12])[CH:3]=1.Cl.Cl[C:15]1[N:20]=[C:19]([NH:21][C@@H:22]2[CH2:30][C@H:29]3[N:25]([CH2:26][CH2:27][CH2:28]3)[C:24]([CH3:32])([CH3:31])[CH2:23]2)[C:18]([F:33])=[CH:17][N:16]=1.CC1C=CC(S(O)(=O)=O)=CC=1.O>CC(O)C>[Cl:12][C:4]1[CH:3]=[C:2]([NH:1][C:15]2[N:20]=[C:19]([NH:21][C@@H:22]3[CH2:30][C@H:29]4[N:25]([CH2:26][CH2:27][CH2:28]4)[C:24]([CH3:31])([CH3:32])[CH2:23]3)[C:18]([F:33])=[CH:17][N:16]=2)[CH:11]=[CH:10][C:5]=1[O:6][CH2:7][CH2:8][OH:9]参加物
5
