Hydrochloric Acid → 4-Chloro-2,6-difluoroaniline hydrochloride
反応式
Cl.C(OC([NH:9][C:10]1[C:15]([F:16])=[CH:14][C:13]([Cl:17])=[CH:12][C:11]=1[F:18])=O)(C)(C)C>C(OCC)(=O)C>[ClH:17].[Cl:17][C:13]1[CH:14]=[C:15]([F:16])[C:10]([NH2:9])=[C:11]([F:18])[CH:12]=1参加物
4
実験手順
A saturated solution of hydrogen chloride in ethyl acetate (4 ml) was added to N-t-butoxycarbonyl-4-chloro-2,6-difluoroaniline (330 mg, 1.3 mmol) and the mixture stirred at ambient temperature for 2 hours. The precipitate was collected by filtration to give 4-chloro-2,6-difluoroaniline hydrochloride (140 mg, 56%).
後処理
- filtrationThe precipitate was collected by filtration
出典と根拠
- ORDレコード
- ord-1b183999590949a6af8eb197931caed8
- 出典データセット
- uspto-grants-2001_02
- 特許番号
- US06184225B2
反応ノート
読み込み中…