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HRID 635304作成日：2026年10月26日

N-(oxan-4-ylidene)hydroxylamine → 3-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-6,7-dihydro-4H-pyrano[4,3-c]isoxazole

https://huagongshe.com/reaction/635304

反応式

関与物質

役割名称HCID仕込み量
反応物N-(oxan-4-ylidene)hydroxylamineHCID 12298558—
反応物Ethyl 4-(4-(4-fluorophenyl)piperazin-1-yl)-n-butyrateHCID 14879737—
生成物3-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-6,7-dihydro-4H-pyrano[4,3-c]isoxazoleHCID 17773089—

反応手順

By the same reaction and treatment as in Example 48 using tetrahydro-4H-pyran-4-one oxime and ethyl 4-(4-(4-fluorophenyl)piperazin-1-yl)-n-butyrate, 3-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-6,7-dihydro-4H-pyrano[4,3-c]isoxazole is obtained.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06187774B1
出典データセットuspto-grants-2001_02
ORD IDord-1e4743d0791249f28f4d40409e991df5
出典メモuspto-grants-2001_02