Diethyl ethylmalonate → 2-Amino-2-ethyl-4-(4-octylphenyl)butanol

HRID 635478ノート

反応式

HRID 635478 の反応式
C([O:4][CH2:5][C:6]([NH:26]C(=O)C)([CH2:24][CH3:25])[CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([C:15](=O)[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[CH:11][CH:10]=1)(=O)C.C(OC(=O)C(CC)C(OCC)=O)C>>[NH2:26][C:6]([CH2:24][CH3:25])([CH2:7][CH2:8][C:9]1[CH:10]=[CH:11][C:12]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[CH:13][CH:14]=1)[CH2:5][OH:4]

参加物

3

反応物 2

HCID 8610Diethyl ethylmalonateHCID 53718772HCID 53718772、化合物

生成物 1

HCID 226187412-Amino-2-ethyl-4-(4-octylphenyl)butanol

実験手順

In working example 77, 2-acetamido-2-ethyl-4-(4-octanoylphenyl)butyl acetate obtained by using ethylmalonic acid diethyl ester instead of propylmalonic acid diethyl ester, is subjected to reduction in the same manner as working example 2 (7) and then hydrolysis in the same manner as working example 78 to give the subject compound.

後処理

  1. customobtained
  2. customhydrolysis in the same manner
  3. customto give the subject compound

出典と根拠

ORDレコード
ord-3d73f6e20225411fb67d8301ad89e7e7
出典データセット
uspto-grants-2001_02
特許番号
US06187821B1

反応ノート

読み込み中…