3-(Trifluoromethyl)aniline → (3-(Trifluoromethyl)phenyl)hydrazine

HRID 637319

反応式

HRID 637319 の反応式
[NH2:1][C:2]1[CH:3]=[C:4]([C:8]([F:11])([F:10])[F:9])[CH:5]=[CH:6][CH:7]=1.[N:12]([O-])=O.[Na+]>O.Cl>[F:11][C:8]([F:9])([F:10])[C:4]1[CH:3]=[C:2]([NH:1][NH2:12])[CH:7]=[CH:6][CH:5]=1

参加物

5

反応物 2

HCID 73753-(Trifluoromethyl)anilineHCID 23668193Sodium Nitrite

生成物 1

HCID 98650(3-(Trifluoromethyl)phenyl)hydrazine

試薬・触媒・溶媒 2

HCID 313Hydrochloric Acid溶媒2 回HCID 962Water溶媒

実験手順

m-Aminobenzotrifluoride (48.34 g: 0.3 mole) was cooled and treated with concentrated hydrochloric acid (137 ml) added dropwise. The paste was stirred at 0° and a solution of sodium nitrite (19.1 g) in water (137 ml) was added at 0°-5° with stirring. An almost clear solution was obtained. Then a solution of stannous chloride dihydrate (191.3 g) in concentrated hydrochloric acid (137 ml) was added dropwise with stirring at 0°-10°.

後処理

  1. additionadded dropwise
  2. stirringwith stirring
  3. customAn almost clear solution was obtained
  4. stirringwith stirring at 0°-10°

出典と根拠

ORDレコード
ord-d5c0c161ef6a41f88e4b63776bbf63ea
出典データセット
uspto-grants-1985_12
特許番号
US04556671

関連ノート

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