Dimethylformamide → 6-(6-Hydroxyhexyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone

HRID 637898

反応式

HRID 637898 の反応式
CN(C)[CH:3]=[O:4].[OH:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]1[C:18]([OH:19])=[C:17]([O:20][CH3:21])[C:16]([O:22][CH3:23])=[CH:15][C:14]=1C>O=O.C1C=C(C=NCCN=CC2C([O-])=CC=CC=2)C([O-])=CC=1.[Co+2]>[OH:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]1[C:18](=[O:19])[C:17]([O:20][CH3:21])=[C:16]([O:22][CH3:23])[C:3](=[O:4])[C:14]=1[CH3:15]

参加物

5

反応物 2

HCID 6228DimethylformamideHCID 202546196-(6-Hydroxyhexyl)-2,3-dimethoxy-5-methylphenol

生成物 1

HCID 128814636-(6-Hydroxyhexyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone

試薬・触媒・溶媒 2

HCID 26517Salcomine触媒HCID 977Oxygen溶媒

実験手順

To a dimethylformamide solution (20 ml) of 6-(6-hydroxyhexyl)-2,3-dimethoxy-5-methylphenol (1.5 g) is added bis(salicylidene)ethylenediiminocobalt(II) (15 mg), and the mixture is stirred in oxygen streams at atmospheric temperature and pressure for 72 hours. The reaction product is isolated as in Example 7 and purified by silica gel column chromatography. The ether-hexane (1:1) eluate yields 6-(6-hydroxyhexyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone (1.1 g) as orange-yellow oil.

後処理

  1. customThe reaction product is isolated as in Example 7
  2. custompurified by silica gel column chromatography

出典と根拠

ORDレコード
ord-462b9c8a36eb47669301e031c10faa9d
出典データセット
uspto-grants-1985_12
特許番号
US04559177

関連ノート

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