関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | 4-Methyloxybenzyl chloride | HCID 69993 | — |
| 反応物 | Thiobarbituric acid | HCID 2723628 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 4,6-Dihydroxy-2-(4-methoxybenzylsulfanyl)pyrimidine | HCID 178491709 | 54.5% |
反応手順
To a suspension of thiobarbituric acid (15 g) in 50% ethanol (180 ml) are added a solution of NaOH (5.1 g) in 50% ethanol (75 ml) and p-methoxybenzyl chloride (18.7 g). The mixture is heated under stirring for 60' at 60° C.; then it is cooled and the solid is filtered by suction, washed with water; then dried over CaCl2, yielding 15 g of 2-p-methoxy-benzylthio-4,6-dihydroxypyrimidine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04559345 |
|---|
| 出典データセット | uspto-grants-1985_12 |
|---|
| ORD ID | ord-5d6de63010204f47b9d61cc676dd9f97 |
|---|
| 出典メモ | uspto-grants-1985_12 |
|---|
