Ammonium Hydroxide → HCID 21779937、化合物

HRID 638199ノート

反応式

HRID 638199 の反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:13])[CH:9]=[C:10]([CH3:12])[NH2:11])=[CH:4][CH:3]=1.BrC1C=CC([C:21](=O)[CH2:22][C:23](=[O:25])C)=CC=1.[OH-].[NH4+]>CO>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([C:9]2[CH:21]=[CH:22][C:23](=[O:25])[NH:11][C:10]=2[CH3:12])=[O:13])=[CH:6][CH:7]=1

参加物

5

反応物 3

HCID 14923Ammonium HydroxideHCID 4326531-(4-bromophenyl)butane-1,3-dioneHCID 70354817HCID 70354817、化合物

生成物 1

HCID 21779937HCID 21779937、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

The intermediate 3-(4-bromophenyl)-1-methyl-3-oxo-1-propenamine, m.p. 126°-128° C., 56.8 g, was prepared following the procedure described in Example A-2 using 83 g of 1-(4-bromophenyl)-1,3-butanedione, 750 ml of methanol and 100 ml of concentrated aqueous ammonium hydroxide solution. The solid residue after stripping the reaction mixture to dryness on a rotary evaporator was treated with 500 ml of boiling n-hexane, the mixture allowed to stand at room temperature overnight, and, the product collected and dried at room temperature.

後処理

  1. customon a rotary evaporator
  2. additionwas treated with 500 ml of boiling n-hexane
  3. customthe product collected
  4. customdried at room temperature

出典と根拠

ORDレコード
ord-09cfda5caa9548a083e3ae9ec189222a
出典データセット
uspto-grants-1985_12
特許番号
US04560691

反応ノート

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