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HRID 638288作成日:2026年10月27日

N-methylpiperidine-4-carboxamide → 1-[6-Fluoro-2-(4-chlorophenyl)-4-quinolinyl]-N-methyl-4-piperidinecarboxamide

https://huagongshe.com/reaction/638288

反応式

関与物質

役割名称HCID仕込み量
反応物N-methylpiperidine-4-carboxamideHCID 2760460—
反応物4-Chloro-2-(4-chlorophenyl)-6-fluoroquinolineHCID 13603895—
生成物1-[6-Fluoro-2-(4-chlorophenyl)-4-quinolinyl]-N-methyl-4-piperidinecarboxamideHCID 20253658—

反応手順

The named compound was made in a manner analogous to that of Example 4(c) using 4-chloro-2-(4-chlorophenyl)-6-fluoroquinoline, prepared as described in Example 4(b), and N-methylisonipecotamide as starting materials. It was obtained as colorless needles, mp 279°-282°dec on recrystallization from pyridine.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US04560692
出典データセットuspto-grants-1985_12
ORD IDord-628f7fed6f23474d894b2aaff018b534
出典メモuspto-grants-1985_12