関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | N-Acetyl-L-leucine | HCID 70912 | — |
| 反応物 | N-Acetylisoleucine | HCID 7036275 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | L-Leucine | HCID 6106 | — |
反応手順
86.6 grams of this mixture of equal parts of N-acetyl-leucine and N-acetyl-isoleucine were suspended in 400 ml of water and adjusted to pH 7.0 with 50% aqueous sodium hydroxide. There were added 50 mg of CoCl2X6H2O and 50 mg of commerical pig kidney acylase (1200 U/mg) and the mixture was filled up to 500 ml with water. The clear solution was stirred at 36° C. for 6 hours. By filtering with suction, washing and drying there were obtained 17.9 grams of pure L-leucine having a rotary value of [α]D25 =+15.9°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04562153 |
|---|
| 出典データセット | uspto-grants-1985_12 |
|---|
| ORD ID | ord-1d3a85980dba4ee1a0ce9052fe130086 |
|---|
| 出典メモ | uspto-grants-1985_12 |
|---|
