化工社化工社 化学情報印刷レポート · 研究参考用
(4-Bromobutoxy)benzene → 1-(2-Phenoxyethyl)piperazine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (4-Bromobutoxy)benzene | HCID 70986 | — |
| 反応物 | 1-Piperazinecarboxaldehyde | HCID 82191 | — |
| 溶媒 | Isopropanol | HCID 3776 | — |
| 生成物 | 1-(2-Phenoxyethyl)piperazine | HCID 233187 | — |
反応手順
The procedure of Example 2 was repeated in entirety substituting 57.0 g (0.27 moles) of 2-bromoethyl phenyl ether for 4-phenoxybutyl bromide, using 61.6 g (0.54 moles) of 1-formylpiperazine in 300 ml of 2-propanol and refluxing the mixture for 8 hours. Evaporation of the final dried chloroform extracts gave 35 g of 1-[2-phenoxyethyl]piperazine as an oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04562189 |
| 出典データセット | uspto-grants-1985_12 |
| ORD ID | ord-dad50e4304ca4efda3bc70ede21fbfed |
| 出典メモ | uspto-grants-1985_12 |