(Allylamino)-6-methoxy-4-phenylisoquinoline-3-carbonitrile → 1-[(3R,4R)-3,4-dihydroxypyrrolidin-1-yl]-6-methoxy-4-phenylisoquinoline-3-carbonitrile
反応式
C(N[C:5]1[C:14]2[C:9](=[CH:10][C:11]([O:15][CH3:16])=[CH:12][CH:13]=2)[C:8]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[C:7]([C:23]#[N:24])[N:6]=1)C=C.[OH:25][C@H:26]1[C@H:30]([OH:31])[CH2:29][NH:28][CH2:27]1>>[OH:25][C@H:26]1[C@H:30]([OH:31])[CH2:29][N:28]([C:5]2[C:14]3[C:9](=[CH:10][C:11]([O:15][CH3:16])=[CH:12][CH:13]=3)[C:8]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[C:7]([C:23]#[N:24])[N:6]=2)[CH2:27]1参加物
3
実験手順
Following the procedure for 1-(allylamino)-6-methoxy-4-phenylisoquinoline-3-carbonitrile, using (3R,4R)-3,4-dihydroxypyrrolidine in place of allylamine, the title compound was synthesized.
出典と根拠
- ORDレコード
- ord-d5fd2007d7234af9a061bec98f7b66c7
- 出典データセット
- uspto-grants-2010_04