関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Glycolic Acid | HCID 757 | — |
| 反応物 | (+-)-3-Phenyllactic acid | HCID 3848 | — |
| 反応物 | HCID 178418581 | HCID 178418581 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | Benzyl 2-hydroxyacetate | HCID 561337 | — |
反応手順
Construction of Benzyl-glycolic Acid. Glycolic acid (7.69,100 mmols) is added to N,N'-diisopropylbenzylisourea (23.39,100 mmols) with stirring for 1 hour. The volume is then increased to 200 mL with THF, and the mixture stirred for 48 h at room temperature. After cooling the mixture to -15° C., the diisopropylurea is removed by filtration and the THF evaporated under reduced pressure. The resulting product is pumped under high vacuum for 24 h to give benzyl glycolate which may be used without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05248761 |
|---|
| 出典データセット | uspto-grants-1993_09 |
|---|
| ORD ID | ord-5c317f14cf624df39c513f9852247f2b |
|---|
| 出典メモ | uspto-grants-1993_09 |
|---|
