1-(Bromomethyl)naphthalene → HCID 58900231、化合物

反応式

C[O:2][C:3]([C:5]1[NH:6][C:7]2[C:12]([CH:13]=1)=[CH:11][CH:10]=[C:9]([CH3:14])[CH:8]=2)=[O:4].Br[CH2:16][C:17]1[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH:20]=[CH:19][CH:18]=1>>[CH3:14][C:9]1[CH:8]=[C:7]2[C:12]([CH:13]=[C:5]([C:3]([OH:2])=[O:4])[N:6]2[CH2:16][C:17]2[C:26]3[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=3)[CH:20]=[CH:19][CH:18]=2)=[CH:11][CH:10]=1

参加物

反応物 2

HCID 1378441-(Bromomethyl)naphthalene

HCID 4715128methyl 6-methyl-1H-indole-2-carboxylate

生成物 1

HCID 58900231HCID 58900231、化合物

実験手順

Using general procedure B, 6-methyl-1H-indole-2-carboxylic acid methyl ester was coupled with 1-bromomethyl-naphthalene and the product obtained was hydrolyzed to give the title compound as a white solid. MS: 314.1 ([M−H]−).

後処理

customthe product obtained

出典と根拠

ORDレコード: ord-5e6c4962f7c94a6f8acfa2d0c2ab6b82
出典データセット: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07696240B2

反応ノート

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