Hydrochloric Acid → 3-aminomethyl-5-fluoro-1-naphthalen-1-ylmethyl-1H-indole-2-carboxylic acid hydro-chloride
反応式
C([O:3][C:4]([C:6]1[N:7]([CH2:18][C:19]2[C:28]3[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=3)[CH:22]=[CH:21][CH:20]=2)[C:8]2[C:13]([C:14]=1[CH2:15][NH2:16])=[CH:12][C:11]([F:17])=[CH:10][CH:9]=2)=[O:5])C.[ClH:29]>>[ClH:29].[NH2:16][CH2:15][C:14]1[C:13]2[C:8](=[CH:9][CH:10]=[C:11]([F:17])[CH:12]=2)[N:7]([CH2:18][C:19]2[C:28]3[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=3)[CH:22]=[CH:21][CH:20]=2)[C:6]=1[C:4]([OH:5])=[O:3]参加物
3
実験手順
3-Aminomethyl-5-fluoro-1-naphthalen-1-ylmethyl-1H-indole-2-carboxylic acid ethyl ester; salt with hydrogen chloride was hydrolyzed as described in the general procedure B (Exp. 2.2) to give 3-aminomethyl-5-fluoro-1-naphthalen-1-ylmethyl-1H-indole-2-carboxylic acid hydro-chloride as an off-white solid. MS: 347.4 ([M−H]−).
出典と根拠
- ORDレコード
- ord-2b3705df65d34e4b876ff92530d1b91f
- 出典データセット
- uspto-grants-2010_04
- DOI