5-Hexynoic acid → 6-[3-(2-Hydroxy-1-methyl-ethylcarbamoyl)phenyl]-hex-5-ynoic acid

関与物質

役割	名称	HCID	仕込み量
反応物	5-Hexynoic acid	HCID 143036	—
反応物	N-(2-hydroxy-1-methyl-ethyl)-3-iodobenzamide	HCID 23730076	—
生成物	6-[3-(2-Hydroxy-1-methyl-ethylcarbamoyl)phenyl]-hex-5-ynoic acid	HCID 11358215	99%

The iodobenzamide (1)(2.00 g, 6.5 mmol) was coupled with 5-hexynoic acid using method B yielding (4)(1.87 g, 6.42 mmol; 99% yield).