関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 2-Bromo-1-(3-nitrophenyl)ethan-1-one | HCID 75213 | — |
| 反応物 | HCID 178513497 | HCID 178513497 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | HCID 178513496 | HCID 178513496 | 11.4% |
反応手順
A mixture of 5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carboxamide (29.4 mg, 0.1 mmol) and 2-bromo-1-(3-nitrophenyl)ethanone (24.4 mg, 0.1 mmol) in EtOH (2 mL) was stirred at 80° C. for 16 hr. The mixture was filtered to afford 5 mg of crude 2-(3-nitrophenyl)-6-(4-phenoxyphenyl)-1H-imidazo[1,2-b]pyrazole-7-carboxamide as a yellow solid. MS (ESI) m/e [M+1]+ 440.0.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US09447106B2 |
|---|
| 出典データセット | uspto-grants-2016_09 |
|---|
| ORD ID | ord-ee2d4ce594704a0985377a363f5590cf |
|---|
| 出典メモ | uspto-grants-2016_09 |
|---|
