Chloromethyl Methyl Ether → HCID 177621498、化合物

温度

5 °C

A 30.0 g quantity of N,N diethyl-N-methvlamine (reagent, product of Tokyo Kasei Co., Ltd.) was dissolved in 120 g of toluene, followed by nitrogen replacement. Over a period of 1 hour, 31.2 g of chloromethyl methyl ether (reagent, product of Tokyo Kasei Co., Ltd.) was added dropwise to the solution at 5° C. The mixture was stirred at 5° C. for 1 hour, heated to a gradually elevated temperature and stirred at room temperature for 10 hours to complete the reaction. The reaction mixture was filtered, and the solids obtained were washed with 150 g of toluene and 150 g of acetone and then dried in a vacuum, giving 53.7 g of the desired product (white solid).

1. temperatureheated to a gradually elevated temperature
2. stirringstirred at room temperature for 10 hours
3. customthe reaction
4. filtrationThe reaction mixture was filtered
5. customthe solids obtained
6. washwere washed with 150 g of toluene and 150 g of acetone
7. customdried in a vacuum

ORDレコード

ord-2577b84cc177486b9b1012e05d9563ea

出典データセット

uspto-grants-2010_04

DOI

10.6084/m9.figshare.5104873.v1

特許番号

US07700243B2