Hydrochloric Acid → HCID 85875172、化合物
反応式
C(=O)([O-])O.[K+].Cl[CH2:7][C:8]([NH:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][C:16]([OH:18])=[O:17])=[O:9].[C-:19]#[N:20].[K+].Cl>O>[C:19]([CH2:7][C:8]([NH:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][C:16]([OH:18])=[O:17])=[O:9])#[N:20]参加物
6
実験手順
2.8 g (20 mmol) potassium hydrogen carbonate were added to 8.3 g (40 mmol) 6-(chloracetamido) hexanoic acid dissolved in 25 ml water. 3.2 g (48 mmol) potassium cyanide was then added to the clear solution which was cooled on ice. The reaction mixture was stirred for 17 hours and was then acidified with HCl (2N). The residue after extraction was purified by chromatography (silica gel, solvent: ethyl acetate).
後処理
- temperaturewas cooled on ice
- extractionThe residue after extraction
- customwas purified by chromatography (silica gel, solvent: ethyl acetate)
出典と根拠
- ORDレコード
- ord-89a04f08e9d6410690e8f9eb18855139
- 出典データセット
- uspto-grants-2010_04
- 特許番号
- US07700306B2
反応ノート
読み込み中…