Hexane → N-(4-tert-Butylphenyl)-N'-[2-(1H-indol-2-yl)phenyl]urea

HRID 643982

反応式

HRID 643982 の反応式
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[C:2]1[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[NH2:16].[C:17]([C:21]1[CH:26]=[CH:25][C:24]([N:27]=[C:28]=[O:29])=[CH:23][CH:22]=1)([CH3:20])([CH3:19])[CH3:18].CCCCCC>ClCCl>[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[C:2]1[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[NH:16][C:28]([NH:27][C:24]1[CH:25]=[CH:26][C:21]([C:17]([CH3:20])([CH3:19])[CH3:18])=[CH:22][CH:23]=1)=[O:29]

参加物

5

反応物 3

HCID 8058HexaneHCID 7359662-(2-Aminophenyl)indoleHCID 27356951-Tert-butyl-4-isocyanatobenzene

生成物 1

HCID 16092112N-(4-tert-Butylphenyl)-N'-[2-(1H-indol-2-yl)phenyl]urea

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

To a solution of commercially available 2-(1H-indol-2-yl)benzenamine (62 mg, 0.3 mmol) in dichloromethane (1.5 mL) at rt was added 4-tert-butylphenyl isocyanate (30 mg, 0.171 mmol). The reaction was stirred overnight at rt. Hexane (1 mL) was added to the reaction mixture and the reaction was allowed to set for ˜5 min. Example 1 was the solid formed which was collected by filtration (47.3 mg). (M+H)+=384.37.

後処理

  1. waitto set for ˜5 min
  2. customformed which
  3. filtrationwas collected by filtration (47.3 mg)

出典と根拠

ORDレコード
ord-f708b8748d114bc9b9f41b1b12c4132f
出典データセット
uspto-grants-2010_04
特許番号
US07700620B2

関連ノート

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