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Ethyl bromopyruvate → Ethyl 6-isopropylimidazo[1,2-a]pyridine-2-carboxylate Ethyl 6-isopropylimidazo[1,2-a]pyridine-2-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl bromopyruvate | HCID 66144 | — |
| 反応物 | 5-(Propan-2-yl)pyridin-2-amine | HCID 17985805 | — |
| 生成物 | Ethyl 6-isopropylimidazo[1,2-a]pyridine-2-carboxylate Ethyl 6-isopropylimidazo[1,2-a]pyridine-2-carboxylate | HCID 68684722 | — |
反応手順
15.1 Ethyl 6-isopropylimidazo[1,2-a]pyridine-2-carboxylate Ethyl 6-isopropylimidazo[1,2-a]pyridine-2-carboxylate is prepared by condensing 2-amino-5-isopropylpyridine (PCT Int. Appl. WO 2005028444) with ethyl 3-bromopyruvate according to the method described by J. G. Lombardino in J. Org. Chem. (1965), 30(7), 2403.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07704989B2 |
| 出典データセット | uspto-grants-2010_04 |
| ORD ID | ord-caf591e82d37441da6909407ecc77d62 |
| 出典メモ | uspto-grants-2010_04 |