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Benzyl mercaptan → 2-Benzylthio-4-(2-chloro-4-trifluoromethylphenoxy)nitrobenzene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzyl mercaptan | HCID 7509 | — |
| 反応物 | Sodium hydride | HCID 24758 | — |
| 反応物 | Benzene, 2-chloro-1-(3,4-dinitrophenoxy)-4-(trifluoromethyl)- | HCID 156238 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 2-Benzylthio-4-(2-chloro-4-trifluoromethylphenoxy)nitrobenzene | HCID 20236281 | — |
反応手順
1.7 g of benzyl mercaptan was dissolved in dry tetrahydrofuran and 0.5 g of sodium hydride added with stirring under dry nitrogen. The reaction mixture was stirred under reflux for 30 minutes, and a solution of 5 g of 1A dissolved in 25 ml of dry tetrahydrofuran was added dropwise. Reaction occurred rapidly, and the product was chromatographically purified to give 2-benzylthio-4-(2-chloro-4-trifluoromethylphenoxy)nitrobenzene (1B) as a yellow oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04609394 |
| 出典データセット | uspto-grants-1986_09 |
| ORD ID | ord-a90262bdbc264b34851ba14fae0a069f |
| 出典メモ | uspto-grants-1986_09 |