2-(2,6-Dimethylmorpholin-4-yl)nicotinonitrile → [2-(2,6-Dimethylmorpholin-4-yl)pyridin-3-yl]methylamine

HRID 645590ノート

反応式

HRID 645590 の反応式
[CH3:1][CH:2]1[O:7][CH:6]([CH3:8])[CH2:5][N:4]([C:9]2[N:16]=[CH:15][CH:14]=[CH:13][C:10]=2[C:11]#[N:12])[CH2:3]1>[Ni]>[CH3:1][CH:2]1[O:7][CH:6]([CH3:8])[CH2:5][N:4]([C:9]2[C:10]([CH2:11][NH2:12])=[CH:13][CH:14]=[CH:15][N:16]=2)[CH2:3]1

参加物

3

反応物 1

HCID 685821892-(2,6-Dimethylmorpholin-4-yl)nicotinonitrile

生成物 1

HCID 16795690[2-(2,6-Dimethylmorpholin-4-yl)pyridin-3-yl]methylamine

試薬・触媒・溶媒 1

HCID 935Nickel触媒

実験手順

The product of Example 134A and Raney/nickel were processed according to the method of Example 13° C. to provide the product. MS (ESI+) m/z 222 (M+H)+;

後処理

  1. customwere processed according to the method of Example 13° C.
  2. customto provide the product

出典と根拠

ORDレコード
ord-0872e4ed2ea1487f82f35a575013a5de
出典データセット
uspto-grants-2010_04
特許番号
US07704997B1

反応ノート

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