Hydrochloric Acid → HCID 178498971、化合物
反応式
CO[C:3]([CH2:5][C:6]([CH2:8][C:9]([O:11][CH3:12])=[O:10])=[O:7])=[O:4].C([O-])(=O)C.[Na+].[F:18][C:19]([F:23])([F:22])[C:20]#[N:21].Cl>C(O)C>[OH:7][C:6]1[CH:5]=[C:3]([OH:4])[N:21]=[C:20]([C:19]([F:23])([F:22])[F:18])[C:8]=1[C:9]([O:11][CH3:12])=[O:10]参加物
6
実験手順
To a well stirred mixture of 84.35 g (0.484 mol) of dimethyl acetonedicarboxylate, 200 ml of saturated sodium acetate, and 400 ml of ethanol at 70° C. was passed 49 g of trifluoroacetonitrile in 4 hours. The reaction mixture was cooled and poured into a mixture of 100 ml of concentrated HCl and 1000 g of ice. The insoluble material was collected to give 28.7 g (25%) of product: mp 235°-238.5° C. (dec).
後処理
- customin 4 hours
- temperatureThe reaction mixture was cooled
- customThe insoluble material was collected
出典と根拠
- ORDレコード
- ord-3f55da22bdb94cf3aba76b0db2de418f
- 出典データセット
- uspto-grants-1986_09
- 特許番号
- US04609399
反応ノート
読み込み中…