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Benzaldehyde → 2-[(5-Fluoro-3-methyl-1H-indol-2-yl)-phenyl-methyl]-3-hydroxy-4-methyl-4-phenyl-cyclobut-2-enone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzaldehyde | HCID 240 | — |
| 反応物 | 5-Fluoro-3-methyl-1H-indole | HCID 22351503 | — |
| 反応物 | 2-Methyl-2-phenyl-cyclobutane-1,3-dione | HCID 68581027 | — |
| 生成物 | 2-[(5-Fluoro-3-methyl-1H-indol-2-yl)-phenyl-methyl]-3-hydroxy-4-methyl-4-phenyl-cyclobut-2-enone | HCID 54762047 | — |
反応手順
Using general procedure C, 2-methyl-2-phenyl-cyclobutane-1,3-dione (Lit. 1) was reacted with benzaldehyde and 5-fluoro-3-methyl-1H-indole to give the title compound as a colorless solid. MS: 410.3 ([M−H]−).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07705034B2 |
| 出典データセット | uspto-grants-2010_04 |
| ORD ID | ord-d1ab97c69cc84845a555228cf8864fce |
| 出典メモ | uspto-grants-2010_04 |