関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 3,5-Dimethylphenol | HCID 7948 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | 1,4-Dichlorobutanol | HCID 19347542 | — |
| 生成物 | 4-Chloro-1-(3,5-dimethylphenoxy)-2-butanol | HCID 13120344 | — |
反応手順
To a mixture of 245 g. (2 moles) of 3,5-dimethylphenol and 2 liters of 2N sodium hydroxide was added 2.5 moles of 1,4-dichlorobutanol with stirring at 65° C. overnight. The solid precipitate which separated on cooling was filtered and washed with water to neutrality. Recrystallization with isopropyl ether yielded 375 g. of white crystalline solid which melted at 74°-76° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04609735 |
|---|
| 出典データセット | uspto-grants-1986_09 |
|---|
| ORD ID | ord-ac41ec0c18c44ca8a3fe37648a717c89 |
|---|
| 出典メモ | uspto-grants-1986_09 |
|---|
