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3,5-Dichloro-4-fluoroaniline → N-[(3,5-dichloro-4-fluorophenyl)-carbamoyl]-2-methylalanine methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3,5-Dichloro-4-fluoroaniline | HCID 75948 | — |
| 反応物 | Methyl 2-isocyanato-2-methylpropanoate | HCID 2769374 | — |
| 生成物 | N-[(3,5-dichloro-4-fluorophenyl)-carbamoyl]-2-methylalanine methyl ester | HCID 20439133 | — |
反応手順
3-(3,5-dichloro-4-phenyl)-5,5-dimethylhydantoin, which melts at 175°-176°, is obtained in the manner indicated in Example 1 from 3,5-dichloro-4-fluoro-aniline and 2-isocyanato-2-methylpropionic acid methyl ester and after crystallizing from ether/petroleum ether. The N-[(3,5-dichloro-4-fluorophenyl)-carbamoyl]-2-methylalanine methyl ester intermediately formed is not isolated.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04407814 |
| 出典データセット | uspto-grants-1983_10 |
| ORD ID | ord-58628825cad64a3ea3319cdf6ad7b0cf |
| 出典メモ | uspto-grants-1983_10 |